***Named best-seller in 2003/2004 by Pharmaceutical and Medicinal Chemistry Journal***
1. A. Avdeef, Absorption and Drug Development: Solubility, Permeability and Charge State 2003, 287 pages, ISBN 0-471-42365-3.
 

Helps drug discovery professionals to eliminate poorly absorbable molecules early in the drug discovery process, which can save drug companies millions of dollars.
Extensive tabulations, in appendix format, of properties and structures of about 200 standard drug molecules can be found in the book.

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2. Avdeef, A. Drug Ionization and Physicochemical Profiling. In: Mannhold, R. (Ed.), Molecular Drug Properties: Measurement and Prediction, Wiley-VCH, 2007, pp. 55-83, ISBN: 978-3-527-31755-4.
 

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3. Avdeef, A.; Voloboy, D.; Foreman, A. Dissolution and Solubility. In: B. Testa, H. van de Waterbeemd (eds.), Comprehensive Medicinal Chemistry II, Volume 5: ADME-TOX Approaches, Elsevier: Oxford, UK, 2007, pp. 399-423, ISBN 0-08-044513-6.
 

Comprehensive Medicinal Chemistry II is designed as an essential reference work for medicinal chemists and also for scientists and workers in the broader area of pharmaceutical and biotechnology sciences.

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4. Avdeef, A. HT Solubility and Permeability: MAD-PAMPA Analysis. In: B. Testa, S.D. Krämer, H. Wunderli-Allenspach, G. Folkers (eds.), Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies, Wiley-VCH: Weinheim, 2006, pp. 221-241, ISBN 978-3-90639-035-2.
 

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5. Avdeef, A.; Ruell, J.A. Absorption using the PAMPA Approach. In: Z. Yan, G.W. Caldwell (eds.), Optimization in Drug Discovery: In Vitro Methods, The Humana Press: Totowa, NJ, 2004, pp. 37-64, ISBN 1-58829-332-7.
 

A panel of researchers and experts from leading universities and major pharmaceutical companies from all over the world systematically describe cutting-edge experimental protocols for the early in vitro evaluation of new chemical entities (NCE).

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6. Avdeef, A. High-throughput Measurement of Membrane Permeability. In: H. van de Waterbeemd, H. Lennernäs, P. Artursson (eds.), Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability, Wiley-VCH: Weinheim, 2003, pp. 46-71, ISBN 3-527-30438-X.
 

Written by an international team from academia and the pharmaceutical industry, this book covers all aspects of the oral bioavailability of medicines. The focus is placed on methods for determining the parameters relevant to bioavailability.

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7. Avdeef, A. High-throughpur Measurements of Solubility Profiles. In: B. Testa, H. van de Waterbeemd, G. Folkers, R. Guy (eds.), Pharmacokinetic Optimization in Drug Research: Biological, Physicochemical, and Computational Strategies, Verlag Helvetica Chimica Acta: Zürich and Wiley-VCH: Weinhem, 2001, pp. 305-326, ISBN 3-906390-22-5.
 

In this work of unique breadth and depth, internationally recognized authorities from academia and industry present the most modern biological, physicochemical, and computational approaches for optimization of pharmacokinetic properties.

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